Orphans Sabrina and Daphne Grimm are sent to live with an eccentric grandmother that they have always believed to be dead.

With the help of a long lost relative, and a little magic, Sabrina Grimm and her sister Daphne try to find out who has kidnapped their parents and rescue them.

Fairy-tale detectives Sabrina and Daphne Grimm face their first case without Granny Relda's help when the future gets mixed up with the past in Ferryport Landing, and because some of the future does not look bright, Puck helps them try to make some changes.

While running a spy network from their elementary school, five unpopular misfits combine their enhanced abilities and use cutting-edge gadgetry to fight evil around the world.

Hoping to save their family and the citizens of Ferryport Landing from the evil plans of Mirror, Sabrina and Daphne Grimm seek counsel from the other magic mirrors, who advise them to join forces with the Scarlet Hand.

When Ms. Information kidnaps the President's daughter, it is up to twelve-year-old Ruby, also known as Pufferfish, to use her super-nanobyte-enhanced allergies in leading the NERDS' investigation.